Tadalafil, a medication used to treat erectile dysfunction, is sold as Vidalista pills. Because of the relaxation of smooth muscles in penile blood vessels brought on by elevated levels of cGMP, blood flows more readily into the penis. By inhibiting PDE-5, it improves blood flow and prolongs the relaxation of smooth muscle in the penis. This helps to sustain bigger quantities of cGMP in the penis. It is advisable to refrain from taking Vidalista pills in combination with nitrates and alpha-blockers as this may cause a dangerous drop in blood pressure. The Vidalista pills that are available can be taken with plain water. Try not to crush or break up the tablets while you are required to consume them.